Captain Kruise Leeming misses out because of a foot injury suffered in last week's record win at Hull, so Smith will need to make a change at hooker.
He has options with Brad Dwyer, who has been left out of the past two games, included in an initial 20-man squad, alongside fellow hooker Corey Johnson and Jarrod O'Connor who started there the last time Leeming did not feature.
Johnson is in Bradford Bulls' initial squad to play Newcastle Thunder - in Newcastle - on Friday, so the decision would seem to be whether Dwyer starts or is used as an impact player off the bench.
Here's a predicted 17.
13. Cameron Smith (loose-forward)
James Donaldson has started the last couple, but Smith may be recalled to the 13 against his hometown club. Photo: Bruce Rollinson
15. Sam Walters (sub)
Likely to continue as a stand-in prop off the bench. Photo: Allan McKenzie/SWpix.com
16. Jarrod O'Connor (sub)
Can cover several roles in the pack. Photo: John Clifton/SWpix.com
17. Morgan Gannon (sub)
Will surely be in the 17, but may have to start on the bench. Photo: Bruce Rollinson
18. Castleford Tigers
Greg Eden, Bureta Faraimo, Jake Mamo, Mahe Fonua, Derrell Olpherts, Niall Evalds, Danny Richardson, Daniel Smith, Adam Milner, George Griffin, Kenny Edwards, Alex Mellor, Joe Westerman. Subs Liam Watts, George Lawler, Suaia Matagi, Cheyse Blair. Photo: Allan McKenzie/SWpix.com